Project Research Scientist–I
Project Title: Antimicrobial Peptide-Based Inhibition of AgrC as a Novel Strategy to Target Virulence and Antimicrobial Resistance in Staphylococcus aureus
Funding Agency: Indian Council of Medical Research (ICMR) – Investigator Initiated Small Grant
Principal Investigator: Dr. Mrittika Sengupta, Associate Professor, Centre for Life Sciences, Mahindra University
Project Duration: Initially one year (extendable based on performance). The candidate will have the opportunity to register in PhD programme at Mahindra University.
About the Project
This project aims to develop a resistance-sparing anti-virulence strategy against methicillin-resistant Staphylococcus aureus (MRSA) by targeting AgrC using antimicrobial peptides (AMPs). The study integrates computational peptide design, molecular microbiology, biofilm assays, and in vivo validation to identify novel therapeutic candidates that suppress virulence without promoting antimicrobial resistance.
Position Details
Position: Project Research Scientist – I (Non-Medical)
Number of Positions: One
Location:
Centre for Life Sciences at Mahindra University which has major focus in research undertaken by faculty trained in modern technologies such as personalized medicine, genome editing, metabolic engineering, immunobiology, host-pathogen interaction, GMOs, molecular diagnostics, nanobiotechnology, bioprocess modelling, biosensors, green products, stem cells & regenerative medicine, biomaterials, biomedical devices, computational biology, clinical informatics, etc.
Application deadline:
February 20th, 2026
Qualification:
M.Sc. / M. Tech in Microbiology, Biotechnology, Microbiology, Life Sciences, Molecular Biology or related disciplines.
Desirable Skills
- Hands-on experience in microbiology, qRT-PCR, biofilm studies.
- Familiarity with antimicrobial resistance research.
- Strong background in microbiology and molecular biology.
- Experience with computational peptide design desirable
- Prior experience in handling mouse models desirable
Fellowship
As per ICMR norms: Project Research Scientist–I (Non-Medical) @ Rs. 56,000/- P.M. + HRA 30% @ 16,800/-P.M.
The position is purely temporary and co-terminus with the project.
How to Apply
Interested candidates should email their CV, a brief statement of interest, and contact details of two referees to the Principal Investigator.
Email: mrittika.sengupta@mahindrauniversity.edu.in
Subject line: Application for Project Research Scientist-I- ICMR Project (AgrC-AMPs) Shortlisted candidates will be informed via email for interview.
