Arun Khattri

Arun Khattri is an Associate Professor at the Centre for Life Sciences, Mahindra University. He earned his Ph.D. in Life Sciences from CSIR–Centre for Cellular and Molecular Biology (CCMB), Hyderabad, and has extensive expertise in cancer biology, functional genomics, computational biology, and biomarker discovery.

Prior to joining Mahindra University, he served as a Ramalingaswami Fellow at IIT-BHU and later as Distinguished Expert and Dean at the Uttar Pradesh State Institute of Forensic Science. His research primarily focuses on head and neck cancer genomics, integrating bioinformatics and functional genomics approaches to uncover molecular mechanisms and therapeutic targets. He has authored several impactful publications in reputed international journals and actively mentors undergraduate, postgraduate, and doctoral researchers.

• Ph.D. in Life Sciences, CSIR–Centre for Cellular and Molecular Biology, Hyderabad, 2010
• MSc Biotechnology, Jawaharlal Nehru University, New Delhi
• PG Diploma (Advanced) in Bioinformatics, Jawaharlal Nehru Univerisity, New Delhi

• Tiwari AK, Jain D, Tiwari JK, Kishore S, Singh AK, Srivastava RS, Shrivastava SK, Khattri A* (2025). “Deciphering Oral Cancer Subtypes: Integrating Differential Gene Expression and Pathway Analysis Followed by Non-Negative Matrix Factorization Transcription Analysis.” Oral Oncology Reports, 14, 100735. https://doi.org/10.1016/j.oor.2025.100735 (Corresponding Author).
• Khattri A*, Sheikh N, Agarwal N, Kaushik S, Kochanny S, Ginat D, Lingen MW, Blair E, Seiwert TY* (2024). “Switching Anti-EGFR Antibody Re-Sensitizes Head and Neck Cancer Patient Following Acquired Resistance to Cetuximab.” Cancer Gene Therapy, 31, 1477–1485. https://doi.org/10.1038/s41417-024-00812-5 (Corresponding Author).
• Tiwari JK, Negi S, Kashyap M, Nizamuddin S, Singh A, Khattri A* (2022). “Pan-Cancer Analysis Shows Enrichment of Macrophages, Overexpression of Checkpoint Molecules, Inhibitory Cytokines, and Immune Exhaustion Signatures in EMT-High Tumors.” Frontiers in Oncology, 11, 793881. https://doi.org/10.3389/fonc.2021.793881 (Corresponding Author).
• Goel B, Tiwari AK, Pandey RK, Singh AP, Kumar S, Sinha A, Jain SK, Khattri A* (2022). “Therapeutic Approaches for the Treatment of Head and Neck Squamous Cell Carcinoma – An Update on Clinical Trials.” Translational Oncology, 21, 101426. https://doi.org/10.1016/j.tranon.2022.101426 (Corresponding Author).
• Tiwari JK, Tripathi N, Srivastava RS, Kumar S, Singh S, Jain SK, Khattri A* (2022). “Low Expression of TMPRSS2 – A SARS-CoV-2 Internalization Protease – Associates with Basal Subtype of Head and Neck Squamous Cell Carcinoma.” Translational Oncology, 22, 101458. https://doi.org/10.1016/j.tranon.2022.101458 (Corresponding Author).
• Nag S, Mandal A, Joshi A, Jain N, Srivastava RS, Singh S, Khattri A* (2022). “Sialyltransferases and Neuraminidases: Potential Targets for Cancer Treatment.” Diseases, 10, 114. https://doi.org/10.3390/diseases10040114 (Corresponding Author).
• Tiwari JK, Sheikh N, Khattri A*. “SIGLECs: Novel Immunotherapy Targets Enriched in Inflamed-Mesenchymal Subtype of Head and Neck Cancers.” (Manuscript under preparation) (Corresponding Author).
• Khattri A, Pandey R, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K (2009). “Estrogen Receptor β Gene Mutations in Indian Infertile Men.” Molecular Human Reproduction, 15(8), 513–520. https://doi.org/10.1093/molehr/gap044
• Khattri A, Pandey RK, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K (2009). “APOB Gene Signal Peptide Deletion Polymorphism is not Associated with Infertility in Indian Men.” Journal of Andrology, 30, 734–738. https://doi.org/10.2164/jandrol.109.007898
• Khattri A, Pandey RK, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K (2009). “CA Repeat and RsaI Polymorphisms in ERβ Gene are not Associated with Infertility in Indian Men.” International Journal of Andrology, 32(1), 81–87. https://doi.org/10.1111/j.1365-2605.2007.00821.x
• Khattri A, Bhushan SS, Sireesha V, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K (2011). “The TNP1 Haplotype – GCG is Associated with Azoospermia.” International Journal of Andrology, 34(2), 173–182. https://doi.org/10.1111/j.1365-2605.2010.01072.x
• Khattri A, Reddy V, Pandey RK, Sudhakar DV, Gupta NJ, Chakravarty B, Deenadayal M, Singh L, Thangaraj K (2012). “Novel Mutations in Calcium/Calmodulin-Dependent Protein Kinase IV (CAMK4) Gene in Infertile Men.” International Journal of Andrology, 35(6), 810–818. https://doi.org/10.1111/j.1365-2605.2012.01302.x
• Khattri A, Zuo Z, Brägelmann J, Keck MK, El Dinali M, Brown CD, Stricker T, Munagala A, Cohen EE, Lingen MW, White KP, Vokes EW, Seiwert TY (2014). “Rare Occurrence of EGFRvIII Deletion in Head and Neck Squamous Cell Carcinoma.” Oral Oncology, 51(1), 53–58. https://doi.org/10.1016/j.oraloncology.2014.08.014

Google Scholar Profile: https://scholar.google.com/citations?hl=en&user=FSVgYkQAAAAJ&view_op=list_works&sortby=pubdate

• Associate Professor, Centre for Life Sciences, Mahindra University.
• Distinguished Expert (equivalent to Professor of Practice) & Dean School of Forensic Science, Uttar Pradesh State Institute of Forensic Science, Lucknow, India Aug 2024 – Jul 2025
• Ramalingaswami Fellow (Equivalent to Assistant Professor), IIT-BHU, Varanasi Nov 2018 – Jul 2024

Areas of research interests are Cancer Biology, Functional Genomics, Computational Biology, Cancer Biomarkers Discovery