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Sebastian Uppapalli

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Dr. Sebastian Uppapalli specializes in thermo-fluid sciences, addressing both fundamental and applied engineering challenges through multiphysics simulations. His research spans Newtonian and complex fluid behavior in microfluidics, electrohydrodynamics, and biofluid dynamics. His work includes electro- and magneto-phoresis, supercritical flows, and thermal systems. His industry contributions include the design and development of low-GWP refrigeration systems for tropical climates and an underwater autonomous vehicle platform as a versatile test bed. His current focus is on microfluidic cooling, lab-on-chip platforms, and drug delivery in microscale flows.

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Sebastian Uppapalli

Associate Professor, Faculty Member, Fluidics and Heat Transfer Laboratory

Dr. Sebastian Uppapalli works in Thermo-Fluid sciences, focusing on both fundamental and applied engineering problems. He applies multiphysics simulations to study the flow behavior of Newtonian, non-Newtonian, and complex fluids in microfluidics, electrohydrodynamics, and biofluid dynamics. He has contributed to air quality studies and development of modular power systems in his previous positions.

  • Ph.D. –University of Nevada, Las Vegas (2014)
  • M.S. – UNR (2003)

  • Effects of Gas Embolism on Pulsatile Flow Characteristics Within a Human Carotid Artery, Journal of Biomechanical Engineering, 2022, DOI: 10.1115/1.4054679.
  • Systems Engineering V-Cycle Approach for Design and Development of Autonomous Underwater Vehicle, Oceans Conference Record (IEEE), 2021, DOI: 10.23919/OCEANS44145.2021.9705756.
  • Low-Head In-Stream Hydroelectric Power System, Earth and Space 2018: Engineering for Extreme Environments – Proceedings of the 16th Biennial International Conference on Engineering, Science, Construction, and Operations in Challenging Environments, 2018, DOI: 10.1061/9780784481899.114.
  • The Influence of Particle Size and Residual Charge on Electrostatic Interactions Between Charged Colloidal Particles at an Oil-Water Interface, Soft Matter, 2014, DOI: 10.1039/c4sm00527a.
  • Polarization of a Diffuse Soft Particle Subjected to an Alternating Current Field, Langmuir, 2012, DOI: 10.1021/la301889e.
  • Dust Emissions Created by Low-Level Rotary-Winged Aircraft Flight Over Desert Surfaces, Atmospheric Environment, 2010, DOI: 10.1016/j.atmosenv.2009.12.018.
  • Effect of Soil Type and Momentum on Unpaved Road Particulate Matter Emissions from Wheeled and Tracked Vehicles, Aerosol Science and Technology, 2010, DOI: 10.1080/02786820903516844.
  • In-Plume Emission Test Stand 2: Emission Factors for 10- to 100-kW U.S. Military Generators, Journal of the Air and Waste Management Association, 2009, DOI: 10.3155/1047-3289.59.12.1446.
  • Particulate Emissions from U.S. Department of Defense Artillery Backblast Testing, Journal of the Air and Waste Management Association, 2007, DOI: 10.3155/1047-3289.57.5.551.
  • Renewable Hydrogen Based Off-Grid Power System Control System, Proceedings of the Solar World Congress 2005: Bringing Water to the World, Including Proceedings of 34th ASES Annual Conference and Proceedings of 30th National Passive Solar Conference, 2005.

ORCID: https://orcid.org/0000-0003-0805-7290

  • Associate Professor, Department of Mechanical and Aerospace Engineering, Mahindra University – August 2022 to Present
  • Assistant Professor, Department of Mechanical and Aerospace Engineering,  Mahindra University – July 2017 to August 2022
  • Sr. Mechanical Engineer, Ion Power Group, US – January 2016 – December 2021
  • Research Associate, Energy Systems Lab (2009–2010)
  • Application Engineer, STS LLC (2008–2009)
  • Research Engineer, Desert Research Institute (2004–2008)

Dr. Sebastian Uppapalli has been involved in basic and applied research, in the broad areas of thermal-fluid sciences. His work covers a wide range of domains related to fluid dynamics, microfluidics, and thermal systems, from investigating electro-and-magneto-phoresis in microchannels to studying convective flows of supercritical fluids, as well as designing lab-on-chip systems and developing low GWP refrigeration systems. 

His areas of research interest are Microfluidics and Lab-on-Chip Systems; Bio-fluid Dynamics & Complex Fluids; Electrohydrodynamics & Electrokinetic Phenomena; Computational Fluid Dynamics (CFD) and Multiphysics Simulation

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