Priyadarshini

Priyadarshini is an assistant professor at the Center for Life Sciences, Mahindra University. She did her PhD from Jaypee University of Information Technology, Solan, where she isolated and characterized a novel protein inhibitor of calcium oxalate monohydrate crystals from human renal calculi.

After her PhD, she served as faculty at Jaypee University of Information Technology, Solan and Jaypee Institute of Information Technology, Noida. Under her supervision 2 PhD scholars and 12 M Tech students completed their research work. She has several research publications of national and international repute.

• Ph.D. From Jaypee University of Information Technology, Solan, HP on “Identification and characterization of a calcium oxalate crystal growth protein inhibitor from human renal stone matrix”: (2005-2010)
• M. Sc. From Ranchi University, Ranchi in Zoology with specialization in Ichthyology: (1997-1999)
• 3 years B. Sc. From Ranchi University, Ranchi in Zoology with Honours: (1994-1997)

• Rohan Shinkre Priyanka Verma, Namita A. Raytekar, Maher Ali Rusho, Priyadarshini, Anupama Shetter, “Emerging biomarkers in cancer diagnosis and prognosis: Novel approaches for precision oncology” 2024, Onkologia i Radioterapia, Volume 18, Issue 9
• Faujdar C, Priyadarshini. Comparative study of hydroalcoholic extracts of Bryophyllum pinnatum and Macrotyloma uniflorum for their antioxidant, antiurolithiatic, and wound healing potential. J Appl Biol Biotech. 2022;10(01):196-205. ISSN Print: 2455-7005, ISSN Online: 2347-212X [Scopus indexed]
• Faujdar, C., & Priyadarshini, Investigating the Effect of Hydroalcoholic Extract of Ocimum sanctum on In-vitro Calcium Oxalate Crystallization. Current Trends in Biotechnology and Pharmacy, 2022, 15(6), 47–52, ISSN22307303,09738916 [Scopus Indexed]
• Sharma, N., Gupta, S. Gupta, M., Priyadarshini, & Chandra, S. Transfer Learning-Based Attention Gated Siamese Network for Human and SARS-CoV-2 Protein Interactions. Current Trends in Biotechnology and Pharmacy, 2022, 15(6), 80–82. ISSN 22307303, 09738916 [Scopus Indexed]

• Faujdar, C., & Priyadarshini. Evaluation of In-vitro Cytoprotective, Wound Healing and Antioxidant Effects of Ocimum sanctum Leaf Extract. Current Trends in Biotechnology and Pharmacy, 2021, 15(3), 248–255. ISSN 22307303, 09738916
• Priyadarshini; Negi, Abhishek; Faujdar, Chetna; Nigam, Lokesh; Subbarao, Naidu, “Exploring the Molecular Level Interaction of Human Serum Albumin with Calcium Oxalate Monohydrate Crystals” Protein and Peptide Letters, Volume 28, Number 11, 2021, pp. 1281-1289(9), ISSN 09298665, 18755305
• Manavi Jain, Paramveer Yadav, Priyadarshini. “Proteomics study in Urolithiasis”. Current Proteomics, 2020, vol. 17, Issue 2, 88 – 94, ISSN: 1875-6247 (Online) ISSN: 1570-1646 (Print)
• Priyadarshini, Devesh Raizada, Pragya Kumar, Tanya Singh, Trisha Pruthi, Abhishek Negi, Lokesh Nigam, Naidu Subbarao. Exploring the modulatory effect of albumin on calcium phosphate crystallization. Current Science, 2019, vol. 117, Issue 6, 1083-1089, ISSN 0011-3891
• Nancy Taneja and Priyadarshini. “Mass Spectrometric Analysis of Proteins of L6 Skeletal Muscle Cells under Different Glucose Conditions and Vitamin D Supplementation”. Protein & Peptide Letters, 2018, vol. 25, Issue 4, 356 – 361, ISSN 09298665, 18755305
• D. Raizada, P. Kumar, T. Singh, T. Pruthi, Priyadarshini. “Albumin and its role in urolithiasis”. Asian J Pharm Clin Res, 2017, vol. 10, Issue 10, 32-35.
• Abhishek Negi, Shahrukh Husain, Priyadarshini, “A Review on Role of miRNA in Kidney Diseases” Journal of Global Pharma Technology. 2017; vol. 5, 28-36.
• Priyadarshini, K. Jain, R. Sood. “Evaluation of renal epithelial cell protein under stress condition”. Int J Pharm Pharm Sci, 2016, vol. 8, 337-340. ISSN: 0975-1491 ISSN: 2656-0097
• Priyadarshini, K. Jain. “Cytoprotective effect of Ocimum extract on injured renal epithelial cells”. Int J Pharm Pharm Sci, 2015, vol. 7, 15-18. ISSN: 0975-1491 ISSN: 2656-0097
• K. Aggarwal, S. Tandon, P. Pathak, S. K. Singh, C. Tandon. “Identification of Novel Antilithiatic Cationic Proteins From Human Calcium Oxalate Renal Stone Matrix by MALDI TOF MS,” European Urology Supplements, 2012, vol. 11, e850-e850a ISSN 1569-9056
• Priyadarshini, P.K. Naik, D Sengupta., S.K. Singh, C. Tandon. “Mode of interaction of calcium oxalate crystal with human phosphate cytidylyltransferase 1: a novel inhibitor purified from human renal stone matrix”. Journal of Biomedical Science and Engineering, 2011, vol. 4, 591-598. Print: 1937-6871 Online: 1937-688X
• Priyadarshini, S.K. Singh, C. Tandon. “Effect of biomolecules from human renal stone matrix of calcium oxalate monohydrate stones on in vitro calcium phosphate crystallization”. International Brazilian Journal of Urology, 2010, vol. 36, 621-62, 2010. ISSN 1677-6119, 1677-5538
• Priyadarshini, S.K. Singh, C. Tandon. “Mass spectrometric identification of human phosphate cytidyltransferse 1 as a novel calcium oxalate crystal growth inhibitor purified from human renal stone matrix”.Clinica Chimica Acta, 2009, vol.408, 34-38

Google Scholar: https://scholar.google.com/citations?user=xGDZHKwAAAAJ&hl=en

ORCID: https://orcid.org/0000-0002-8424-6467

• 2023 – Present Assistant Professor Center for Life Sciences Mahindra University.
• Associate Professor JIIT Noida, UP – (2022-2023)
• Assistant Professor (Senior Grade) JIIT Noida, UP – (2016-2022)
• Assistant Professor (Grade II)JIIT Noida, UP
• Lecturer JIIT Noida, UP: (2011-2012)
• Lecturer JUIT, Waknaghat, HP – (2010-2011)
• Associate Lecturer JUIT, Waknaghat, HP – (January 2010-July 2010)

Priyadarshini’s research focuses on understanding the molecular and cellular mechanisms underlying kidney stone disease (urolithiasis) and related metabolic disorders, with particular emphasis on proteomics, medical biotechnology, and phytotherapy. Her work explores the identification and characterization of bioactive phytocompounds with therapeutic potential against renal and metabolic diseases using both computational and experimental approaches.

Her key research interests include proteomics and biomarker discovery for identifying disease mechanisms and diagnostic markers; phytotherapy and natural product research for evaluating the antiurolithiatic, antioxidant, and anti-inflammatory properties of medicinal plants; computational biology and drug design using molecular docking, molecular dynamics simulations, and ADMET modeling; and the study of cellular and molecular mechanisms involved in renal diseases, including oxidative stress, mitochondrial dysfunction, and protein crystallization in renal epithelial cells. She is also interested in translational and integrative biotechnology, bridging computational screening with in vitro validation to develop safe and effective therapeutic strategies for kidney-related and metabolic disorders.