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Dr. Sebastian Uppapalli specializes in thermo-fluid sciences, addressing both fundamental and applied engineering challenges through multiphysics simulations. His research spans Newtonian and complex fluid behavior in microfluidics, electrohydrodynamics, and biofluid dynamics. His work includes electro- and magneto-phoresis, supercritical flows, and thermal systems. His industry contributions include the design and development of low-GWP refrigeration systems for tropical climates and an underwater autonomous vehicle platform as a versatile test bed. His current focus is on microfluidic cooling, lab-on-chip platforms, and drug delivery in microscale flows.
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Sebastian Uppapalli
Associate Professor, Faculty Member, Fluidics and Heat Transfer Laboratory, MU
Dr. Sebastian Uppapalli works in Thermo-Fluid sciences, focusing on both fundamental and applied engineering problems. He applies multiphysics simulations to study the flow behavior of Newtonian, non-Newtonian, and complex fluids in microfluidics, electrohydrodynamics, and biofluid dynamics. He has contributed to air quality studies and development of modular power systems in his previous positions.
- Ph.D. – UNLV (2014)
- M.S. – UNR (2003)
- Warrier, S. R., Reddy, D. S. H., Bada, S., Achampeta, R., Uppapalli, S., & Dontabhaktuni, J. (2024). On-board classification of underwater images using hybrid classical-quantum CNN-based method. Quantum Machine Intelligence, 6(2), 70.
- Nalla, S. K. K., & Uppapalli, S. (2022). Effects of gas embolism on pulsatile flow characteristics within a human carotid artery. Journal of Biomechanical Engineering, 144(11), 111005.
- Uppapalli, S., & Zhao, H. (2014). The influence of particle size and residual charge on electrostatic interactions between charged colloidal particles at an oil–water interface. Soft Matter, 10(25), 4555-4560.
- Uppapalli, S., & Zhao, H. (2012). Polarization of a diffuse soft particle subjected to an alternating current field. Langmuir, 28(30), 11164-11172.
- Associate Professor, Department of Mechanical and Aerospace Engineering, Mahindra University – August 2022 to Present
- Assistant Professor, Department of Mechanical and Aerospace Engineering, Mahindra University – July 2017 to August 2022
- Sr. Mechanical Engineer, Ion Power Group, US – January 2016 – December 2021
Dr. Sebastian Uppapalli has been involved in basic and applied research, in the broad areas of thermal-fluid sciences. His work covers a wide range of domains related to fluid dynamics, microfluidics, and thermal systems, from investigating electro-and-magneto-phoresis in microchannels to studying convective flows of supercritical fluids, as well as designing lab-on-chip systems and developing low GWP refrigeration systems.
His present focus is on investigating drug delivery mechanisms in complex microscale flows, Heat dissipation in electronic chips through microfluidic cooling systems, design of lab-on-chip platforms for life sciences.
