Computational Biology

Computational biology is the application of computer science, statistics, and mathematics to not only store, analyse and utilize biological information but also uncover new biological knowledge through computational approaches to develop products of commercial value in medical, pharmaceutical, industrial and agricultural industries, academia, and clinics.

Overview

Computational Biology

Computational biology is the application of computer science, statistics, and mathematics to not only store, analyse and utilize biological information but also uncover new biological knowledge through computational approaches to develop products of commercial value in medical, pharmaceutical, industrial and agricultural industries, academia, and clinics.

The global computational biology and bioinformatics market is projected to reach USD 21.8 billion by 2026 from USD 10.7 billion in 2021, growing at a CAGR of 15.2%

The field includes foundations in computer science (algorithm design, AI/ML), applied mathematics, statistics, biochemistry, molecular biology, genetics, genomics, biophysics, ecology, evolution, anatomy, neuroscience, etc.

eHR: India will digitise country’s health care delivery system by building registries of healthcare providers and facilities, providing unique health identity to all residents, and ensuring universal access to health care through healthcare informatics

Established companies in biotech, biomedical, pharmaceutical and hundreds of startups are struggling to find trained computational biologists or bioinformaticians.

The Program will offer 5 specializations for students keen to pursue career in a particular domain

  • Healthcare Informatics: The Indian healthcare sector is expected to record a three-fold rise, growing at a CAGR of 22% between 2016–2022 to reach US$ 372 billion in 2022. The need for healthcare informatics (HI) has emerged to store and manage huge data regarding various therapeutics and diagnosis methods in clinical practice across the globe. Major players in healthcare informatics market are Accuro Healthcare Solutions, Allscripts, Agfa HealthCare Corp, Axiom Resource Management Inc., Cardinal Health, Cerner Corp., Benchmark Systems, CNSI, Cognizant Technology Solutions, Companion Technologies, and many more.
  • Computational Genomics: The global precision medicine market size valued at USD 66.1 billion in 2021 is expected to reach USD 175.64 billion by 2030 and poised to grow at a compound annual growth rate (CAGR) of 11.5% during the forecast period 2022 to 2030. The increasing use of pharmacogenomic research for the development of precision medicine, and the increasing partnerships and collaborations between various life sciences and informatics companies for the development of advanced bioinformatics tools and software are major factors contributing to the growth of computational genomics.
  • Computer-Aided Drug Discovery: The global computer-aided drug discovery market is expected to be valued at $7,914.2 million by 2028, surging from $2,741.1 million in 2020 at a noteworthy CAGR of 15.0%. Emerging concepts of artificial intelligence (AI) and big data in computer-aided drug discovery are driving the market. Artificial intelligence can be significantly utilized in multiple parts of drug discovery value chain such as drug design, chemical synthesis, drug screening, drug repurposing, pharmacology and clinical practice.
  • Computation in Agriculture: The precision farming market is expected to grow from USD 8.5 billion in 2022 to USD 15.6 billion by 2030, at a CAGR of 7.9%. Traditionally agriculture industry was highly dependent on manual labour for different activities; however, with technological advancements, automation is enabling the industry players to achieve high output in less time and inputs. In addition to smart sensors, drones, GPS the use of AI-based applications and tools can help farmers in controlled and accurate farming by providing required information or guidance regarding the use of fertilizers, water management, crop rotation, pest control, type of crop to be grown as per soil, nutrition management, optimum planting, etc.
  • Biological Systems Modelling: Biomanufacturing green products in cell factories through synthetic biology would require developing quantitative predictive models of cell metabolism so that biosynthetic pathway engineering interventions can successfully implemented. The biological systems modelling domain, therefore, involves integration of transcriptomic, proteomic, and metabolomic data through machine-learning approaches to predict bioengineering outcomes towards biomanufacturing green products, biomaterials and drugs.

Please CLICK HERE to view Curriculum

Technical Competencies: The program will
deliver following competencies


  • Biological data generation technologies
  • Statistical methods in the context of molecular biology, genomics, medical, and population genetics research
  • Bioinformatics tools and their usage
  • Computing requirements appropriate to solve a given scientific problem (e.g., system, process, algorithm, component or program; define algorithmic time and space complexities and hardware resources required to solve a problem).
  • Command line and scripting based computing skills appropriate to the discipline
  • Construction of software systems of varying complexity based on design and development principles
  • Local and global impact of bioinformatics and genomics on individuals, organizations, and society.
  • Professional, ethical, legal, security, and social issues, and responsibilities in the workplace
  • Effective communication of bioinformatics and genomics problem/issue/topics with a range of audiences
  • Teamwork to accomplish a common scientific goal. Engage in continuing professional development in computational biology

Graduates with a B.Tech. Computational Biology can be recruited as:

  • Genomics:Omics technologies, novel applications of gene/ genome sequencing in diverse biotech domains
  • Data Analysts
  • Application Developers
  • Software Engineers
  • Research Specialists
  • Data Managers
  • Post-graduate studies in computer science, genomics, clinical informatics, etc.

Some of the prominent players operating in the market:


  • Indian Companies
    1. Strand Life Sciences.
    2. Xcode Life Sciences.
    3. Clevergene.
    4. BD Biosciences
    5. Rasa Life Science Informatics
    6. NaturalText
    7. Nucleome Informatics
    8. Biogenick
    9. MarksMan Healthcare Communications
    10. Helix Biosciences
    11. AgriGenome Labs
    12. Genotypic Technology